Price range: $268.00 through $328.00
Background:
BORA is an activator of the protein kinase Aurora A (AURKA; MIM 603072), which is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis (Hutterer et al., 2006 [PubMed 16890155]).[supplied by OMIM, Mar 2008],
| Size | 50μL/100μL |
| Target | BORA |
| Reactivity | Human, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 61kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 440-520 |
| Specificity | BORA Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | BORA C13orf34 |
| Protein Name | Protein aurora borealis (HsBora) |
| Other Name | |
| Species | Human |
| Gene ID | 79866 |
| Uniprot | Q6PGQ7, |
| Species.1 | Mouse |
| Gene ID.1 | 77744 |
| Uniprot.1 | Q8BS90, |
| Species.2 | Rat |
| Gene ID.2 | 306102 |
| Uniprot.2 | Q5M864 |
| Cellular Localization | cytosol,meiotic spindle, |
| Tissue Expression | Bone marrow,Leiomyosarcoma,Rhabdomyosarcoma,Small intestine,Testis carcinom |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Required for the activation of Aurora-A (AURKA/STK6) at the onset of mitosis.,PTM:Phosphorylated by AURKA/STK6.,similarity:Belongs to the BORA family.,subunit:Interacts with AURKA/STK6., |
