Name: BRAF35 Polyclonal Antibody
SKU: WP11298
Price: 268 USD
Availability: InStock

BRAF35 Polyclonal Antibody

Ucallm_WP11298-50

Price range: $268.00 through $328.00

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50μl

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SKU: WP11298-100

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Product details

Background:

function:Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters., sequence caution:Translation N-terminally extended., similarity:Contains 1 HMG box DNA-binding domain., subcellular location:Localized to condensed chromosomes in mitosis in conjunction with BRCA2., subunit:Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Interacts with the BRCA2 tumor suppressor protein., tissue specificity:Ubiquitously expressed in adult tissues.,

Specifications

Size	50μL/100μL
Target	BRAF35
Reactivity	Human, Mouse
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	36kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human HMG20B. AA range:1-50
Specificity	BRAF35 Polyclonal Antibody detects endogenous levels of BRAF35 protein.
Gene Name	HMG20B
Protein Name	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
Other Name	HMG20B; / BRAF35; / HMGX2; / HMGXB2; / SMARCE1R; / SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; / SMARCE1-related protein; / BRCA2-associated factor 35; / HMG box-containing protein 20B; / HMG domain-
Species	Human
Gene ID	10362
Uniprot	Q9P0W2,
Species.1	Mouse
Gene ID.1
Uniprot.1	Q9Z104
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Nucleus. Chromosome. Localized to condensed chromosomes in mitosis in conjunction with BRCA2.
Tissue Expression	Ubiquitously expressed in adult tissues.
Signaling_pathway
Research Areas
Function	Function:Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.,sequence Caution:Translation N-terminally extended.,similarity:Contains 1 HMG box DNA-binding domain.,subcellular location:Localized to condensed chromosomes in mitosis in conjunction with BRCA2.,subunit:Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Interacts with the BRCA2 tumor suppressor protein.,tissue specificity:Ubiquitously expressed in adult tissues.,

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BRAF35 Polyclonal Antibody

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BRAF35 Polyclonal Antibody

Product details

Specifications

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