SKU: WP16176 Categories: ,

BRD1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP16176-100
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Product details

Background:

This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schozophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015],

Specifications

Size50μL/100μL
TargetBRD1
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)116kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human BRD1 AA range: 399-449
SpecificityThis antibody detects endogenous levels of BRD1 at Human
Gene NameBRD1 BRL BRPF2
Protein NameBRD1
Other Name
SpeciesHuman
Gene ID23774
UniprotO95696
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus . Chromosome . Localizes to transcription start sites. .
Tissue ExpressionHighly expressed in testis.
Signaling_pathway
Research Areas
FunctionFunction:Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.,similarity:Contains 1 bromo domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 PWWP domain.,subunit:Component of the MOZ/MORF composed at least of ING5, MYST3/MOZ, MYST4/MORF and one of BRPF1, BRD1/BRPF2 and BRPF3.,tissue specificity:Highly expressed in testis.,
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