Price range: $268.00 through $328.00
Background:
This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | BTF3 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 22kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 120-200 |
| Specificity | BTF3 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | BTF3 NACB OK/SW-cl.8 |
| Protein Name | Transcription factor BTF3 (RNA polymerase B transcription factor 3) |
| Other Name | |
| Species | Human |
| Gene ID | 689 |
| Uniprot | P20290, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q64152 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus . The heterodimer with NACA is cytoplasmic. |
| Tissue Expression | Colon adenocarcinoma,Leukocyte,Skin, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the NAC-beta family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain., |
