SKU: WP11332 Categories: ,

C/EBP γ Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11332-100
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Product details

Background:

The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2011],

Specifications

Size50μL/100μL
TargetC/EBP γ
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)22kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human CEBPG. AA range:31-80
SpecificityC/EBP γ Polyclonal Antibody detects endogenous levels of C/EBP γ protein.
Gene NameCEBPG
Protein NameCCAAT/enhancer-binding protein gamma
Other NameCEBPG; / CCAAT/enhancer-binding protein gamma; / C/EBP gamma
SpeciesHuman
Gene ID1054
UniprotP53567,
Species.1Mouse
Gene ID.112611
Uniprot.1P53568,
Species.2Rat
Gene ID.225301
Uniprot.2P26801
Cellular LocalizationNucleus .
Tissue ExpressionPlacenta,T-cell,Trachea,
Signaling_pathway
Research Areas>>Tuberculosis
FunctionFunction:Transcription factor that binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene. Might change the DNA-binding specificity of other transcription factors and recruit them to unusual DNA sites.,similarity:Belongs to the bZIP family. C/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha and beta and with Fos protein.,
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