SKU: WP8537 Categories: ,

C1orf187 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8537-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetDRAXIN
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)38kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human C1orf187
SpecificityThis antibody detects endogenous levels of C1orf187 at Human, Mouse
Gene NameDRAXIN C1orf187 PSEC0258 UNQ3119/PRO10268
Protein NameDraxin (Dorsal inhibitory axon guidance protein) (Dorsal repulsive axon guidance protein) (Neucrin)
Other Name
SpeciesHuman
Gene ID374946
UniprotQ8NBI3,
Species.1Mouse
Gene ID.170433
Uniprot.1Q6PAL1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted .
Tissue Expression
Signaling_pathway
Research Areas
FunctionChemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
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