SKU: WP15711 Categories: ,

C32 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP15711-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1).[provided by RefSeq, Feb 2011],

Specifications

Size50μL/100μL
TargetC32
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)20kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from Chemokine-like factor at AA range: 103-152
SpecificityC32 Polyclonal Antibody detects endogenous levels of C32 protein.
Gene NameCKLF
Protein NameChemokine-like factor
Other NameCKLF; / CKLF1; / HSPC224; / Chemokine-like factor; / C32
SpeciesHuman
Gene ID51192
UniprotQ9UBR5,
Species.1Mouse
Gene ID.175458
Uniprot.1Q9DAS1,
Species.2Rat
Gene ID.2245978
Uniprot.2Q9JK79
Cellular Localization[Isoform 1]: Secreted .; [Isoform 2]: Membrane; Multi-pass membrane protein .; [Isoform 4]: Membrane; Multi-pass membrane protein .
Tissue ExpressionIsoform 1, isoform 2, isoform 3 and isoform 4 have highest expression levels in adult spleen, lung, testis, ovary, peripheral blood leukocyte, placenta, pancreas, and in fetal brain, skeletal muscle, thymus and heart. Lower expression levels in adult skeletal muscle, liver, thymus colon, prostate and fetal spleen and liver.
Signaling_pathway
Research Areas
FunctionFunction:Isoform CKLF1 has chemotactic response in rat monocytes, neutrophils, and lymphocytes.,Function:May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10.,similarity:Belongs to the chemokine-like factor family.,similarity:Contains 1 MARVEL domain.,tissue specificity:All 4 isoforms have highest expression levels in adult spleen, lungs, testis, ovary, peripheral blood leucocyte, placenta, pancreas, and in fetal brain, skeletal muscle, thymus and heart. Lower expression levels in adult skeletal muscle, liver, thymus colon, prostate, and fetal spleen and liver.,
Please login to post questions
Back to Top
Product has been added to your cart