CA VA Polyclonal Antibody
Ucallm_WP11352-50
Price range: $268.00 through $328.00
Product details
Background:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | CA VA |
| Reactivity | Human |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 35kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CA5A. AA range:171-220 |
| Specificity | CA VA Polyclonal Antibody detects endogenous levels of CA VA protein. |
| Gene Name | CA5A |
| Protein Name | Carbonic anhydrase 5A mitochondrial |
| Other Name | CA5A; / CA5; / Carbonic anhydrase 5A; / mitochondrial; / Carbonate dehydratase VA; / Carbonic anhydrase VA; / CA-VA |
| Species | Human |
| Gene ID | 763 |
| Uniprot | P35218, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P23589 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Mitochondrion . |
| Tissue Expression | Liver,Umbilical cord, |
| Signaling_pathway | |
| Research Areas | >>Nitrogen metabolism; / >>Metabolic pathways |
| Function | Catalytic activity:H(2)CO(3) = CO(2) + H(2)O.,cofactor:Zinc.,Function:Reversible hydration of carbon dioxide.,similarity:Belongs to the alpha-carbonic anhydrase family., |
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