Product details
Background:
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CAPRIN1 rabbit pAb
Ucallm_WP5970-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | CAPRIN1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 78kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human CAPRIN1 |
| Specificity | This antibody detects endogenous levels of CAPRIN1 at Human, Mouse,Rat |
| Gene Name | CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 |
| Protein Name | Caprin-1 (Cell cycle-associated protein 1) (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105) |
| Other Name | |
| Species | Human |
| Gene ID | 4076 |
| Uniprot | Q14444, |
| Species.1 | Mouse |
| Gene ID.1 | 53872 |
| Uniprot.1 | Q60865, |
| Species.2 | Rat |
| Gene ID.2 | 362173 |
| Uniprot.2 | Q5M9G3 |
| Cellular Localization | Cytoplasm, cytosol . Cell projection, dendrite . Cell projection, lamellipodium . Associated with RNA granules. At the leading edge of migrating fibroblasts, colocalizes with DDX3X (PubMed:28733330). . |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | |
| Research Areas | |
| Function | May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs. |
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