Product details
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CASK rabbit pAb
Ucallm_WP8182-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | CASK |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 102kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human CASK |
| Specificity | This antibody detects endogenous levels of CASK at Human, Mouse,Rat |
| Gene Name | CASK LIN2 |
| Protein Name | Peripheral plasma membrane protein CASK (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog) |
| Other Name | |
| Species | Human |
| Gene ID | 8573 |
| Uniprot | O14936, |
| Species.1 | Mouse |
| Gene ID.1 | 12361 |
| Uniprot.1 | O70589, |
| Species.2 | Rat |
| Gene ID.2 | 29647 |
| Uniprot.2 | Q62915 |
| Cellular Localization | Nucleus . Cytoplasm . Cell membrane; Peripheral membrane protein . |
| Tissue Expression | Ubiquitous. Expression is significantly greater in brain relative to kidney, lung, and liver and in fetal brain and kidney relative to lung and liver. |
| Signaling_pathway | |
| Research Areas | |
| Function | Multidomain scaffolding Mg(2+)-independent protein kinase that catalyzes the phosphotransfer from ATP to proteins such as NRXN1, and plays a role in synaptic transmembrane protein anchoring and ion channel trafficking . Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1. Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity). |
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