SKU: WP0978 Categories: ,

CBPA4 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0978-100
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Product details

Background:

This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetCBPA4
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)46kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityCBPA4 Polyclonal Antibody detects endogenous levels of protein.
Gene NameCPA4 CPA3 UNQ694/PRO1339
Protein NameCarboxypeptidase A4 (Carboxypeptidase A3)
Other Name
SpeciesHuman
Gene ID51200
UniprotQ9UI42,
Species.1Mouse
Gene ID.1
Uniprot.1Q6P8K8
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted .
Tissue ExpressionFetal expression in the adrenal gland, brain, heart, intestine, kidney, liver and lung. Except for fetal brain that shows no imprinting, expression was found preferentially from the maternal allele.
Signaling_pathway
Research Areas
Functioncofactor:Binds 1 zinc ion per subunit.,Function:Metalloprotease that could be involved in the histone hyperacetylation pathway.,induction:Up-regulated by inhibitors of histone dacetylation.,similarity:Belongs to the peptidase M14 family.,subunit:Interacts with LXN.,tissue specificity:Fetal expression in the adrenal gland, brain, heart, intestine, kidney, liver and lung. Except for fetal brain that shows no imprinting, expression was found preferentially from the maternal allele.,
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