SKU: WP1981 Categories: ,

CCNI Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1981-100
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Product details

Background:

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetCCNI
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)41kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 30-110
SpecificityCCNI Polyclonal Antibody detects endogenous levels of protein.
Gene NameCCNI
Protein NameCyclin-I
Other Name
SpeciesHuman
Gene ID10983
UniprotQ14094,
Species.1Mouse
Gene ID.1
Uniprot.1Q9Z2V9
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus membrane .
Tissue ExpressionHighest levels in adult heart, brain and skeletal muscle. Lower levels in adult placenta, lung, kidney and pancreas. Also high levels in fetal brain and lower levels in fetal lung, liver and kidney. Also abundant in testis and thyroid.
Signaling_pathway
Research Areas
Functiondevelopmental stage:Expression is independent of the cell cycle in lung fibroblasts.,similarity:Belongs to the cyclin family.,tissue specificity:Highest levels in adult heart, brain and skeletal muscle. Lower levels in adult placenta, lung, kidney and pancreas. Also high levels in fetal brain and lower levels in fetal lung, liver and kidney. Also abundant in testis and thyroid.,
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