CCS Polyclonal Antibody
Ucallm_WP11469-50
Price range: $268.00 through $328.00
Product details
Background:
Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | CCS |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 32kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CCS. AA range:225-274 |
| Specificity | CCS Polyclonal Antibody detects endogenous levels of CCS protein. |
| Gene Name | CCS |
| Protein Name | Copper chaperone for superoxide dismutase |
| Other Name | CCS; / Copper chaperone for superoxide dismutase; / Superoxide dismutase copper chaperone |
| Species | Human |
| Gene ID | 9973 |
| Uniprot | O14618, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9WU84 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases |
| Research Areas | >>Amyotrophic lateral sclerosis; / >>Pathways of neurodegeneration - multiple diseases |
| Function | cofactor:Binds 1 zinc ion per subunit.,cofactor:Binds 2 copper ions per subunit.,Function:Delivers copper to copper zinc superoxide dismutase (SOD1).,similarity:Contains 1 HMA domain.,similarity:In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.,subunit:Homodimer, and heterodimer with SOD1.,tissue specificity:Ubiquitous., |
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