SKU: WN0239 Categories: ,

CD276/B7H3 Nb-FC recombinant antibody [PN0582]

Price range: $699.00 through $799.00

SKU: WN0239-50
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Product details

Background:

The protein encoded byThis gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript ofThis gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR ofThis transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression ofThis protein and miR29 levels, suggesting regulation of expression ofThis gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq, Sep 2011]

Specifications

TargetCD276/B7H3
ReactivityHuman
ApplicationsELISA
MW(Calculated)
MW(Observed)
Host Species
Isotype
Conjugate
ModificationUnmodified
Recommended Dilution RatioELISA 1:5000-100000
CompositionPhosphate-buffered solution
SourceCamel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification ProcessRecombinant Expression and Affinity purified
Purity
Storage Condition-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
ConcentrationPlease check the information on the tube
ClonalityMonoclonal
Clone NumberPN0582
ImmunogenPurified recombinant Human CD276
Sequence
SpecificityThis recombinant monoclonal antibody can detects endogenous levels of CD276/B7H3 protein.
Gene NameCD276 B7H3 PSEC0249 UNQ309/PRO352
Protein NameCD276 antigen (4Ig-B7-H3) (B7 homolog 3) (B7-H3) (Costimulatory molecule) (CD antigen CD276)
AliasCD276;B7H3;PSEC0249;CD276 antigen;4Ig-B7-H3;B7 homolog 3;B7-H3;Costimulatory molecule;CD antigen CD276;CD276 nanobody;B7H3 nanobody;
Organism-1Human
Gene ID-180381.0
SwissProt-1Q5ZPR3
Organism-2
Gene ID-2
SwissProt-2
Organism-3
Gene ID-3
SwissProt-3
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationMembrane ; Single-pass type I membrane protein .
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