SKU: WM1513 Categories: ,

CD56 [ABT500] mouse mAb

Price range: $268.00 through $328.00

SKU: WM1513-50
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Product details

Background:
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011],

Specifications

Size50μL/100μL
TargetCD56
ReactivityHuman, Mouse, Rat
ApplicationsIHC, WB, IF, ELISA
MW(Calculated)95kD
MW(Observed)100kD
Host SpeciesMouse
IsotypeIgG1,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRMM500
ImmunogenSynthesized peptide derived from human CD56 AA range: 500-600
SpecificityThe antibody can specifically recognize human CD56 protein.
Gene NameNCAM1 NCAM
Protein Nameantigen MSK39 identified by monoclonal 5.1H11; antigen recognized by monoclonal 5.1H11; CD56; cell adhesion molecule, neural, 1; MSK 39; MSK39; N-CAM-1; NCAM 1; NCAM; NCAM C; NCAM-1; NCAM1; NCAM1_HUMAN; NCAMC; Neural cell adhesion molecule 1; Neural cell adhesion molecule NCAM; OTTHUMP00000235666
Other Nameantigen MSK39 identified by monoclonal 5.1H11; / antigen recognized by monoclonal 5.1H11; / CD56; / cell adhesion molecule, neural, 1; / MSK 39; / MSK39; / N-CAM-1; / NCAM 1; / NCAM; / NCAM C; / NCAM-1; / NCAM1; / NCAM1_HUMAN; / NCAMC; / Neural cell adhesion molecule 1; / Neural cell adhesion molecule NCAM; / OTTHUMP00000235666
SpeciesHuman
Gene ID4684
UniprotP13591,
Species.1Mouse
Gene ID.1
Uniprot.1P13595,
Species.2Rat
Gene ID.2
Uniprot.2P13596
Cellular LocalizationMembranous, Cytoplasmic
Tissue ExpressionTonsil/ Appendix
Signaling_pathwayHuman Diseases >> Neurodegenerative disease >> Prion disease;Environmental Information Processing >> Signaling molecules and interaction >> Cell adhesion molecules
Research Areas>>Cell adhesion molecules; / >>Prion disease
FunctionFunction:This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.,online information:N-CAM 140,online information:NCAM entry,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,
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