SKU: WP11558 Categories: ,

Cdk10 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11558-100
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Product details

Background:

The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],

Specifications

Size50μL/100μL
TargetCdk10
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)43kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human CDK10. AA range:51-100
SpecificityCdk10 Polyclonal Antibody detects endogenous levels of Cdk10 protein.
Gene NameCDK10
Protein NameCyclin-dependent kinase 10
Other NameCDK10; / Cyclin-dependent kinase 10; / Cell division protein kinase 10; / Serine/threonine-protein kinase PISSLRE
SpeciesHuman
Gene ID8558
UniprotQ15131,
Species.1Mouse
Gene ID.1234854
Uniprot.1Q3UMM4,
Species.2Rat
Gene ID.2361434
Uniprot.2Q4KM47
Cellular LocalizationCytoplasm, cytoskeleton, cilium basal body .
Tissue ExpressionBrain,Colon,Kidney,Lung,
Signaling_pathway
Research Areas
FunctionCatalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,
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