Price range: $268.00 through $328.00
Background:
function:Collaborates with cep110, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in cytokinesis. Required for recruitment of cep110 to the centrosome., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 IQ domain., similarity:Contains 6 LRR (leucine-rich) repeats., subunit:Interacts with CALM1 and CEP110.,
| Size | 50μL/100μL |
| Target | Cep97 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 97kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CEP97. AA range:581-630 |
| Specificity | Cep97 Polyclonal Antibody detects endogenous levels of Cep97 protein. |
| Gene Name | CEP97 |
| Protein Name | Centrosomal protein of 97 kDa |
| Other Name | CEP97; / LRRIQ2; / Centrosomal protein of 97 kDa; / Cep97; / Leucine-rich repeat and IQ domain-containing protein 2 |
| Species | Human |
| Gene ID | 79598 |
| Uniprot | Q8IW35, |
| Species.1 | Mouse |
| Gene ID.1 | 74201 |
| Uniprot.1 | Q9CZ62 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Recruited at the distal end of the mother centriole by MPHOSPH9. . |
| Tissue Expression | Lung,Skin,Testis, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Collaborates with cep110, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in cytokinesis. Required for recruitment of cep110 to the centrosome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 IQ domain.,similarity:Contains 6 LRR (leucine-rich) repeats.,subunit:Interacts with CALM1 and CEP110., |
