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Home/Reagents/Antibody/Primary antibody/Monoclonal Antibody/Mouse mAb/Cytokeratin [ABT154] mouse mAb
SKU: WM1464 Categories: ,

Cytokeratin [ABT154] mouse mAb

Ucallm_WM1464-50

Price range: $268.00 through $328.00

SKU: WM1464-50
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Product details

Background:
Cytokeratin can label keratinized epithelium, stratified squamous epithelium, stratified epithelium, proliferative keratinized cells and monolayer epithelium. It can be used in the study of various cancers. It is positive in various adenocarcinoma, small cell carcinoma, transitional cell carcinoma, malignant mesothelioma, germ cell tumors other than seminoma, leiomyosarcoma and some synovial sarcomas. CEA and EMA can be combined for the differential diagnosis of epithelial tumors and non epithelial tumors.

Specifications

Size50μL/100μL
TargetCytokeratin Pan
ReactivityHuman, Mouse, Rat
ApplicationsIHC, WB, IF, ELISA
MW(Calculated)
MW(Observed)52kD,55kD
Host SpeciesMouse
IsotypeIgG1,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRMM154
ImmunogenSynthesized peptide derived from human Cytokeratin Pan AA range:100-200
SpecificityThe antibody can recognize multiple human Cytokeratins, including CK10, 13, 14, 15, 16, 18, 19, and it can be used for immunohistochemical detection of tumors from monolayer and multilayered epithelium.
Gene NameKRT10; KRT13; KRT14; KRT15; KRT16; KRT19
Protein NameCytokeratin Pan
Other Namepan cytokeRatin; / wide spectrum CytokeRatin; / AE1; / AE3
SpeciesHuman
Gene ID
UniprotP13645;P13646;P02533;P19012;P08779;P08727
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasmic, Membranous
Tissue ExpressionNon-neural epithelial tissues.
Signaling_pathway
Research Areas>>Rap1 signaling pathway; / >>Apelin signaling pathway; / >>Hippo signaling pathway; / >>Cell adhesion molecules; / >>Adherens junction; / >>Bacterial invasion of epithelial cells; / >>Pathways in cancer; / >>Endometrial cancer; / >>Thyroid cancer; / >>Melanoma; / >>Bladder cancer; / >>Gastric cancer
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