Name: DLRB1 Polyclonal Antibody
SKU: WP1096
Price: 268 USD
Availability: InStock

DLRB1 Polyclonal Antibody

Ucallm_WP1096-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP1096-100

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Product details

Background:

This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013],

Specifications

Size	50μL/100μL
Target	DLRB1
Reactivity	Human, Mouse, Rat
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	10kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000; ELISA 1:5000-20000
Formulation	Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from part region of human protein AA range: 1-50
Specificity	DLRB1 Polyclonal Antibody detects endogenous levels of protein.
Gene Name	DYNLRB1 BITH DNCL2A DNLC2A ROBLD1 HSPC162
Protein Name	Dynein light chain roadblock-type 1 (Bithoraxoid-like protein) (BLP) (Dynein light chain 2A, cytoplasmic) (Dynein-associated protein Km23) (Roadblock domain-containing protein 1)
Other Name
Species	Human
Gene ID	83658
Uniprot	Q9NP97,
Species.1	Mouse
Gene ID.1
Uniprot.1	P62627,
Species.2	Rat
Gene ID.2
Uniprot.2	P62628
Cellular Localization	Cytoplasm, cytoskeleton.
Tissue Expression	High expression in heart, liver, brain and pancreas; moderate in placenta, skeletal muscle and kidney; low in lung, prostate, testis, small intestine and colon. Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients.
Signaling_pathway
Research Areas	>>Salmonella infection
Function	Alternative products:Additional isoforms seem to exist,Function:May be involved in assembly and motor function of dynein, which plays a central role in cell division and intracellular transport.,miscellaneous:Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients.,similarity:Belongs to the GAMAD family.,subunit:Homodimer.,tissue specificity:High expression in heart, liver, brain and pancreas; moderate in placenta, skeletal muscle and kidney; low in lung, prostate, testis, small intestine and colon.,