Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | DPP7 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 54kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from the C-terminal region of human DPP7. |
| Specificity | DPP7 Polyclonal Antibody detects endogenous levels of DPP7 protein. |
| Gene Name | DPP7 |
| Protein Name | Dipeptidyl peptidase 2 |
| Other Name | DPP7; / DPP2; / QPP; / Dipeptidyl peptidase 2; / Dipeptidyl aminopeptidase II; / Dipeptidyl peptidase 7; / Dipeptidyl peptidase II; / DPP II; / Quiescent cell proline dipeptidase |
| Species | Human |
| Gene ID | 29952 |
| Uniprot | Q9UHL4, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9ET22 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Lysosome . Cytoplasmic vesicle . Secreted . |
| Tissue Expression | Detected in seminal plasma (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:Release of an N-terminal dipeptide, Xaa-Yaa-|-, preferentially when Yaa is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides.,Function:Plays an important role in the degradation of some oligopeptides.,PTM:N-glycosylated.,similarity:Belongs to the peptidase S28 family.,subunit:Homodimer., |
