Price range: $268.00 through $328.00
Background:
This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | DRAM1 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 26kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 151-200 |
| Specificity | DRAM1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | DRAM1 DRAM |
| Protein Name | DNA damage-regulated autophagy modulator protein 1 (Damage-regulated autophagy modulator) |
| Other Name | |
| Species | Human |
| Gene ID | 55332 |
| Uniprot | Q8N682, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9DC58 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Lysosome membrane; Multi-pass membrane protein . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | autophagy, apoptosis, cell death, programmed cell death, death, |
