Product details
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DRG1 rabbit pAb
Ucallm_WP7183-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | DRG1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 40kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human DRG1 |
| Specificity | This antibody detects endogenous levels of DRG1 at Human, Mouse |
| Gene Name | DRG1 NEDD3 |
| Protein Name | Developmentally-regulated GTP-binding protein 1 (DRG-1) (Neural precursor cell expressed developmentally down-regulated protein 3) (NEDD-3) |
| Other Name | |
| Species | Human |
| Gene ID | 4733 |
| Uniprot | Q9Y295, |
| Species.1 | Mouse |
| Gene ID.1 | 13494 |
| Uniprot.1 | P32233 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Cytoplasm . The DRG1-ZC3H15/DFRP1 complex associates with polysomes. |
| Tissue Expression | High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP . Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions . When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation . Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions . |
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