Price range: $268.00 through $328.00
Background:
The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. This protein may function in the differentiation of oligodendrocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
| Size | 50μL/100μL |
| Target | DUS15 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 32kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human DUS15 AA range: 15-65 |
| Specificity | This antibody detects endogenous levels of DUS15 at Human/Mouse |
| Gene Name | DUSP15 C20orf57 VHY |
| Protein Name | DUS15 |
| Other Name | |
| Species | Human |
| Gene ID | 128853 |
| Uniprot | Q9H1R2, |
| Species.1 | Mouse |
| Gene ID.1 | 252864 |
| Uniprot.1 | Q8R4V2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm .; [Isoform 3]: Cell membrane; Lipid-anchor; Cytoplasmic side. |
| Tissue Expression | Highly expressed in testis (PubMed:15138252). Expressed in brain; up-regulated in patients with multiple sclerosis gray matter lesions (PubMed:22792334). |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,Catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,Caution:Although assigned as two separate genes (c20orf57 and DUSP15), it is probable that C20orf57 does not exist by itself and is a part of the DUSP15 gene.,PTM:Isoform 3 is N-myristoylated.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,tissue specificity:Highly expressed in testis., |
