Name: Epsin 3 Polyclonal Antibody
SKU: WP12228
Price: 268 USD
Availability: InStock

Epsin 3 Polyclonal Antibody

Ucallm_WP12228-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP12228-100

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Product details

Background:

induction:In keratinocytes, by wounding or contact with collagen., similarity:Belongs to the epsin family., similarity:Contains 1 ENTH (epsin N-terminal homology) domain., similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats., subcellular location:Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus., tissue specificity:Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.,

Specifications

Size	50μL/100μL
Target	Epsin 3
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	68kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human EPN3. AA range:401-450
Specificity	Epsin 3 Polyclonal Antibody detects endogenous levels of Epsin 3 protein.
Gene Name	EPN3
Protein Name	Epsin-3
Other Name	EPN3; / Epsin-3; / EPS-15-interacting protein 3
Species	Human
Gene ID	55040
Uniprot	Q9H201,
Species.1	Mouse
Gene ID.1
Uniprot.1	Q91W69
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cytoplasm . Cytoplasm, perinuclear region . Cytoplasmic vesicle, clathrin-coated vesicle . Nucleus . Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.
Tissue Expression	Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.
Signaling_pathway
Research Areas	>>Endocytosis
Function	induction:In keratinocytes, by wounding or contact with collagen.,similarity:Belongs to the epsin family.,similarity:Contains 1 ENTH (epsin N-terminal homology) domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,subcellular location:Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.,tissue specificity:Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.,