Product details
Background:
ESCO2 rabbit pAb
Ucallm_WP7587-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ESCO2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 66kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ESCO2 |
| Specificity | This antibody detects endogenous levels of ESCO2 at Human, Mouse |
| Gene Name | ESCO2 |
| Protein Name | N-acetyltransferase ESCO2 (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2) |
| Other Name | |
| Species | Human |
| Gene ID | 157570 |
| Uniprot | Q56NI9, |
| Species.1 | Mouse |
| Gene ID.1 | 71988 |
| Uniprot.1 | Q8CIB9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Chromosome . Nuclear in interphase cells, excluded from chromosomes during metaphase but reassociates with chromosomes in telophase. . |
| Tissue Expression | Widely expressed in fetal tissues. In adult, it is expressed in thymus, placenta and small intestine. |
| Signaling_pathway | Cellular Processes >> Cell growth and death >> Cell cycle |
| Research Areas | |
| Function | Acetyltransferase required for the establishment of sister chromatid cohesion . Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3 . |
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