Product details
Background:
FBP2 rabbit pAb
Ucallm_WP7361-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | FBP2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 37kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FBP2 |
| Specificity | This antibody detects endogenous levels of FBP2 at Human, Mouse,Rat |
| Gene Name | FBP2 |
| Protein Name | Fructose-1,6-bisphosphatase isozyme 2 (FBPase 2) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 2) |
| Other Name | |
| Species | Human |
| Gene ID | 8789 |
| Uniprot | O00757, |
| Species.1 | Mouse |
| Gene ID.1 | 14120 |
| Uniprot.1 | P70695, |
| Species.2 | Rat |
| Gene ID.2 | 114508 |
| Uniprot.2 | Q9Z1N1 |
| Cellular Localization | Cell junction . Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line. In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca(2+) concentration. . |
| Tissue Expression | Expressed in skeletal muscle (at protein level). |
| Signaling_pathway | Organismal Systems >> Endocrine system >> Insulin signaling pathway;Organismal Systems >> Endocrine system >> Glucagon signaling pathway;Environmental Information Processing >> Signal transduction >> AMPK signaling pathway |
| Research Areas | |
| Function | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate. |
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