Product details
Background:
FBXL15 rabbit pAb
Ucallm_WP8089-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | FBXL15 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 33kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FBXL15 |
| Specificity | This antibody detects endogenous levels of FBXL15 at Human, Mouse,Rat |
| Gene Name | FBXL15 FBXO37 |
| Protein Name | F-box/LRR-repeat protein 15 (F-box only protein 37) |
| Other Name | |
| Species | Human |
| Gene ID | 79176 |
| Uniprot | Q9H469, |
| Species.1 | Mouse |
| Gene ID.1 | 68431 |
| Uniprot.1 | Q91W61, |
| Species.2 | Rat |
| Gene ID.2 | 309453 |
| Uniprot.2 | D4ABB4 |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2. |
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