PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 3 C3H1-type zinc fingers.,
Specifications
Size
50μL/100μL
Target
Fliz1
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)
40kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
The antiserum was produced against synthesized peptide derived from human ZC3H8. AA range:81-130
Specificity
Fliz1 Polyclonal Antibody detects endogenous levels of Fliz1 protein.
Gene Name
ZC3H8
Protein Name
Zinc finger CCCH domain-containing protein 8
Other Name
ZC3H8; / ZC3HDC8; / Zinc finger CCCH domain-containing protein 8
Species
Human
Gene ID
84524
Uniprot
Q8N5P1,
Species.1
Mouse
Gene ID.1
Uniprot.1
Q9JJ48
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus . Colocalizes with coilin in subnuclear cajal and histone locus bodies. Translocates in the LEC complex to cajal and histone locus bodies at snRNA genes in a ICE1-dependent manner. Associates to transcriptionally active chromatin at snRNA genes.
Tissue Expression
Skin,
Signaling_pathway
Research Areas
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 C3H1-type zinc fingers.,