Product details
Background:
function:May be involved in the differentiation of granulocytes and adipocytes., PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the THOC5 family., subcellular location:Shuttles between nucleus and cytoplasm., subunit:Interacts with phosphorylated CSF1R., tissue specificity:Ubiquitously expressed.,





