SKU: WP12323 Categories: ,

FMIP Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12323-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

function:May be involved in the differentiation of granulocytes and adipocytes., PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the THOC5 family., subcellular location:Shuttles between nucleus and cytoplasm., subunit:Interacts with phosphorylated CSF1R., tissue specificity:Ubiquitously expressed.,

Specifications

Size50μL/100μL
TargetFMIP
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)78kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human THOC5. AA range:561-610
SpecificityFMIP Polyclonal Antibody detects endogenous levels of FMIP protein.
Gene NameTHOC5
Protein NameTHO complex subunit 5 homolog
Other NameTHOC5; / C22orf19; / KIAA0983; / THO complex subunit 5 homolog; / Functional spliceosome-associated protein 79; / fSAP79; / NF2/meningioma region protein pK1.3; / Placental protein 39.2; / PP39.2; / hTREX90
SpeciesHuman
Gene ID8563
UniprotQ13769,
Species.1Mouse
Gene ID.1107829
Uniprot.1Q8BKT7,
Species.2Rat
Gene ID.2360972
Uniprot.2Q68FX7
Cellular LocalizationNucleus . Cytoplasm . Shuttles between nucleus and cytoplasm. .
Tissue ExpressionUbiquitously expressed.
Signaling_pathwayGenetic Information Processing >> Translation >> Nucleocytoplasmic transport
Research Areas>>Nucleocytoplasmic transport
FunctionFunction:May be involved in the differentiation of granulocytes and adipocytes.,PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the THOC5 family.,subcellular location:Shuttles between nucleus and cytoplasm.,subunit:Interacts with phosphorylated CSF1R.,tissue specificity:Ubiquitously expressed.,
Please login to post questions
Back to Top
Product has been added to your cart