FMIP Polyclonal Antibody
Ucallm_WP12323-50
Price range: $268.00 through $328.00
Product details
Background:
function:May be involved in the differentiation of granulocytes and adipocytes., PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the THOC5 family., subcellular location:Shuttles between nucleus and cytoplasm., subunit:Interacts with phosphorylated CSF1R., tissue specificity:Ubiquitously expressed.,
Specifications
| Size | 50μL/100μL |
| Target | FMIP |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 78kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human THOC5. AA range:561-610 |
| Specificity | FMIP Polyclonal Antibody detects endogenous levels of FMIP protein. |
| Gene Name | THOC5 |
| Protein Name | THO complex subunit 5 homolog |
| Other Name | THOC5; / C22orf19; / KIAA0983; / THO complex subunit 5 homolog; / Functional spliceosome-associated protein 79; / fSAP79; / NF2/meningioma region protein pK1.3; / Placental protein 39.2; / PP39.2; / hTREX90 |
| Species | Human |
| Gene ID | 8563 |
| Uniprot | Q13769, |
| Species.1 | Mouse |
| Gene ID.1 | 107829 |
| Uniprot.1 | Q8BKT7, |
| Species.2 | Rat |
| Gene ID.2 | 360972 |
| Uniprot.2 | Q68FX7 |
| Cellular Localization | Nucleus . Cytoplasm . Shuttles between nucleus and cytoplasm. . |
| Tissue Expression | Ubiquitously expressed. |
| Signaling_pathway | Genetic Information Processing >> Translation >> Nucleocytoplasmic transport |
| Research Areas | >>Nucleocytoplasmic transport |
| Function | Function:May be involved in the differentiation of granulocytes and adipocytes.,PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the THOC5 family.,subcellular location:Shuttles between nucleus and cytoplasm.,subunit:Interacts with phosphorylated CSF1R.,tissue specificity:Ubiquitously expressed., |
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