Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human FNDC1 AA range: 988-1038
Specificity
This antibody detects endogenous levels of FNDC1 at Human/Rat
Gene Name
FNDC1 FNDC2 KIAA1866 MEL4B3
Protein Name
FNDC1
Other Name
Species
Human
Gene ID
84624
Uniprot
Q4ZHG4,
Species.1
Gene ID.1
Uniprot.1
Species.2
Rat
Gene ID.2
308099
Uniprot.2
Q2Q0I9
Cellular Localization
Secreted .
Tissue Expression
Almost absent from healthy skin; especially in epidermal keratinocytes, skin fibroblasts or endothelial cells and is barely detectable in benign melanocytic naevi. Expressed in the stroma close to skin tumors, in the tumor cells themselves and in the epidermis of psoriasis.
Signaling_pathway
Research Areas
Function
Caution:It is uncertain whether Met-1 or Met-53 is the initiator.,Function:May be an activator of G protein signaling.,induction:By TGF-beta present in the melanoma cell conditioned medium (MCCM).,similarity:Contains 5 fibronectin type-III domains.,tissue specificity:Almost absent from healthy skin; especially in epidermal keratinocytes, skin fibroblasts or endothelial cells and is barely detectable in benign melanocytic naevi. Expressed in the stroma close to skin tumors, in the tumor cells themselves and in the epidermis of psoriasis.,