SKU: WP16568 Categories: ,

FNDC1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP16568-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetFNDC1
ReactivityHuman, Rat
ApplicationsWB
MW(Calculated)208kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human FNDC1 AA range: 988-1038
SpecificityThis antibody detects endogenous levels of FNDC1 at Human/Rat
Gene NameFNDC1 FNDC2 KIAA1866 MEL4B3
Protein NameFNDC1
Other Name
SpeciesHuman
Gene ID84624
UniprotQ4ZHG4,
Species.1
Gene ID.1
Uniprot.1
Species.2Rat
Gene ID.2308099
Uniprot.2Q2Q0I9
Cellular LocalizationSecreted .
Tissue ExpressionAlmost absent from healthy skin; especially in epidermal keratinocytes, skin fibroblasts or endothelial cells and is barely detectable in benign melanocytic naevi. Expressed in the stroma close to skin tumors, in the tumor cells themselves and in the epidermis of psoriasis.
Signaling_pathway
Research Areas
FunctionCaution:It is uncertain whether Met-1 or Met-53 is the initiator.,Function:May be an activator of G protein signaling.,induction:By TGF-beta present in the melanoma cell conditioned medium (MCCM).,similarity:Contains 5 fibronectin type-III domains.,tissue specificity:Almost absent from healthy skin; especially in epidermal keratinocytes, skin fibroblasts or endothelial cells and is barely detectable in benign melanocytic naevi. Expressed in the stroma close to skin tumors, in the tumor cells themselves and in the epidermis of psoriasis.,
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