Price range: $268.00 through $328.00
Background:
function:Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system., similarity:Belongs to the G-protein coupled receptor 1 family.,
| Size | 50μL/100μL |
| Target | FPRL2 |
| Reactivity | Human |
| Applications | IF, ELISA |
| MW(Calculated) | 40kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications; |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FPRL2. AA range:304-353 |
| Specificity | FPRL2 Polyclonal Antibody detects endogenous levels of FPRL2 protein. |
| Gene Name | FPR3 |
| Protein Name | N-formyl peptide receptor 3 |
| Other Name | FPR3; / FPRH1; / FPRL2; / N-formyl peptide receptor 3; / FMLP-related receptor II; / FMLP-R-II; / Formyl peptide receptor-like 2 |
| Species | Human |
| Gene ID | 2359 |
| Uniprot | P25089 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Expression | Detected in various tissues with highest expression in lung. |
| Signaling_pathway | Organismal Systems >> Immune system >> Neutrophil extracellular trap formation |
| Research Areas | >>Neuroactive ligand-receptor interaction; / >>Neutrophil extracellular trap formation; / >>Staphylococcus aureus infection |
| Function | Function:Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family., |
