Need Help? +(1)-866-986-9598
0 My Cart$0.00
Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/Fractalkine Polyclonal Antibody
SKU: WP15401 Categories: ,

Fractalkine Polyclonal Antibody

Ucallm_WP15401-50

Price range: $268.00 through $328.00

SKU: WP15401-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

function:The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1., induction:By TNF and IL-1 in pulmonary endothelial cells and umbilical vein endothelial cells., online information:CX3CL1 entry, PTM:A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form., similarity:Belongs to the intercrine delta family., subunit:Monomer., tissue specificity:Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.,

Specifications

Size50μL/100μL
TargetFractalkine
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)42kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CX3CL1. AA range:231-280
SpecificityFractalkine Polyclonal Antibody detects endogenous levels of Fractalkine protein.
Gene NameCX3CL1
Protein NameFractalkine
Other NameCX3CL1; / FKN; / NTT; / SCYD1; / A-152E5.2; / Fractalkine; / C-X3-C motif chemokine 1; / CX3C membrane-anchored chemokine; / Neurotactin; / Small-inducible cytokine D1
SpeciesHuman
Gene ID6376
UniprotP78423,
Species.1Mouse
Gene ID.1
Uniprot.1O35188
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane; Single-pass type I membrane protein .; [Processed fractalkine]: Secreted .
Tissue ExpressionExpressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level). Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas. Most abundant in the brain and heart.
Signaling_pathwayOrganismal Systems >> Immune system >> Chemokine signaling pathway;Environmental Information Processing >> Signal transduction >> TNF signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction;Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor
Research Areas>>Cytokine-cytokine receptor interaction; / >>Viral protein interaction with cytokine and cytokine receptor; / >>Chemokine signaling pathway; / >>TNF signaling pathway; / >>Human cytomegalovirus infection
FunctionFunction:The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.,induction:By TNF and IL-1 in pulmonary endothelial cells and umbilical vein endothelial cells.,online information:CX3CL1 entry,PTM:A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form.,similarity:Belongs to the intercrine delta family.,subunit:Monomer.,tissue specificity:Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.,
Please login to post questions

Related products
Sku: WR4013
Categories: ,

U-Blot® FOXO3A (Phospho Ser253) Rabbit mAb

0 Reviews
Price range: $288.00 through $368.00
Select options
Mouse lung whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with primary antibody(1:1000). The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.
Sku: WR4002
Categories: ,

U-Blot® Ezrin Rabbit mAb

0 Reviews
Price range: $268.00 through $328.00
Select options
Sku: WR4008
Categories: ,

U-Blot® Hsp90 Rabbit mAb

0 Reviews
Price range: $268.00 through $328.00
Select options
Sku: WR4022
Categories: ,

U-Blot® GSK3 β (Phospho Ser9) Rabbit mAb

0 Reviews
Price range: $288.00 through $368.00
Select options
Sku: WR4011
Categories: ,

U-Blot® Smad2 (Phospho Ser250) Rabbit mAb

0 Reviews
Price range: $288.00 through $368.00
Select options
Western blot analysis of lysates from PT0004R cells, using GAPDH Rabbit mAb. The HRP-conjugated Goat anti-Rabbit IgG antibody (WS0002) was used to detect the antibody.
Sku: WR4001
Categories: ,

U-Blot® GAPDH Rabbit mAb

0 Reviews
Price range: $268.00 through $328.00
Select options

Customer Reviews

  • Shop Categories
Menu
Need Help? +(1)-866-986-9598
Back to Top
Product has been added to your cart