SKU: WP12377 Categories: ,

FTβ Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12377-100
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Product details

Background:

catalytic activity:Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate., cofactor:Binds 1 zinc ion per subunit., function:Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding., similarity:Belongs to the protein prenyltransferase subunit beta family., similarity:Contains 5 PFTB repeats., subunit:Heterodimer of an alpha and a beta subunit.,

Specifications

Size50μL/100μL
TargetFTβ
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)49kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human FNTB. AA range:255-304
SpecificityFTβ Polyclonal Antibody detects endogenous levels of FTβ protein.
Gene NameFNTB
Protein NameProtein farnesyltransferase subunit beta
Other NameFNTB; / Protein farnesyltransferase subunit beta; / FTase-beta; / CAAX farnesyltransferase subunit beta; / Ras proteins prenyltransferase subunit beta
SpeciesHuman
Gene ID2342
UniprotP49356,
Species.1Mouse
Gene ID.1110606
Uniprot.1Q8K2I1,
Species.2Rat
Gene ID.264511
Uniprot.2Q02293
Cellular Localizationcytosol,microtubule associated complex,protein farnesyltransferase complex,
Tissue ExpressionNeuroblastoma,Placenta,Retina,
Signaling_pathway
Research Areas>>Terpenoid backbone biosynthesis
FunctionCatalytic activity:Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.,cofactor:Binds 1 zinc ion per subunit.,Function:Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.,similarity:Belongs to the protein prenyltransferase subunit beta family.,similarity:Contains 5 PFTB repeats.,subunit:Heterodimer of an alpha and a beta subunit.,
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