SKU: WM0727 Categories: ,

H-FABP mouse mAb

Price range: $268.00 through $328.00

SKU: WM0727-50
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Product details

Background:
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

Specifications

Size50μL/100μL
TargetH-FABP
ReactivityHuman(predicted:Mouse
ApplicationssELISA, Detector
MW(Calculated)
MW(Observed)
Host SpeciesMouse
Isotype
Conjugate/ModificationUnmodified
Recommended Dilution RatioELISA 1:10000-20000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone Number14F9
ImmunogenPurified recombinant H-FABP protein expressed in E.coli
Specificity
Gene Namefabp3
Protein Name
Other Name422 protein; / Cardiac Fatty Acid Binding Protein; / FABP 11; / FABP 3; / FABP11; / FABP3; / FABPH_HUMAN; / fatty acid binding protein 11; / Fatty acid binding protein 3; / Fatty acid binding protein 3 muscle and heart; / Fatty acid binding protein 3 muscle and heart mammary derived growth inhibitor; / Fatty acid binding protein 3 muscle; / Fatty acid binding protein 3, muscle and heart; / mammary derived growth inhibitor; / Fatty acid binding protein 3, muscle; / Fatty acid binding protein heart; / Fatty acid binding protein, heart; / Fatty acid binding protein, muscle and heart; / Fatty acid binding protein, skeletal muscle; / Fatty acid-binding protein 3; / Fatty acid-binding protein; / H FABP; / H-FABP; / heart; / Heart type fatty acid binding protein; / Heart-type fatty acid-binding protein; / M FABP; / M-FABP; / mammary derived growth inhibitor; / Mammary-derived growth inhibitor; / MDGI; / Muscle fatty acid binding protein; / Muscle fatty acid-binding protein; / mylein protein P2 homolog; / O FABP; / OTTHUMP00000003898; / P2 adopocyte protein.
SpeciesHuman
Gene ID2170
UniprotP05413,
Species.1Mouse
Gene ID.1
Uniprot.1P11404
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm.
Tissue ExpressionFetal brain cortex,Heart,Liver,Mammary gland,Skeletal muscle,
Signaling_pathwayOrganismal Systems >> Endocrine system >> PPAR signaling pathway
Research Areas>>PPAR signaling pathway
FunctionDomain:Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.,Function:FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,
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