HN1 rabbit pAb
Ucallm_WP6958-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | JPT1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 17kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human HN1 |
| Specificity | This antibody detects endogenous levels of HN1 at Human, Mouse,Rat |
| Gene Name | HN1 ARM2 |
| Protein Name | Hematological and neurological expressed 1 protein (Androgen-regulated protein 2) |
| Other Name | |
| Species | Human |
| Gene ID | 51155 |
| Uniprot | Q9UK76, |
| Species.1 | Mouse |
| Gene ID.1 | 15374 |
| Uniprot.1 | P97825, |
| Species.2 | Rat |
| Gene ID.2 | 287828 |
| Uniprot.2 | Q6AXU6 |
| Cellular Localization | Nucleus . Cytoplasm . |
| Tissue Expression | Expressed in testis, skeletal muscle, thymus, prostate, colon, peripheral blood cells, brain and placenta. |
| Signaling_pathway | |
| Research Areas | |
| Function | Modulates negatively AKT-mediated GSK3B signaling . Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions . Plays a role in the regulation of cell cycle and cell adhesion . Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation . |
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