HSF2B rabbit pAb
Ucallm_WP17417-50
Price range: $268.00 through $328.00
Product details
Background:
HSF2 binding protein (HSF2BP) associates with HSF2. The interaction occurs between the trimerization domain of HSF2 and the amino terminal hydrophilic region of HSF2BP that comprises two leucine zipper motifs. HSF2BP may therefore be involved in modulating HSF2 activation. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | HSF2B |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 37kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human HSF2B AA range: 201-251 |
| Specificity | This antibody detects endogenous levels of HSF2B at Human |
| Gene Name | HSF2BP |
| Protein Name | HSF2B |
| Other Name | |
| Species | Human |
| Gene ID | 11077 |
| Uniprot | O75031 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Chromosome . Localizes on double-strand breaks (DSBs) in mitotic and meiotic chromosomes. . |
| Tissue Expression | Testis specific. Overexpressed in some tumors (PubMed:31242413). |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May be involved in modulating HSF2 activation in testis.,PTM:Sumoylated by UBE2I in response to MEKK1-mediated stimuli.,subunit:Associates with HSF2. The interaction seems to occur between the trimerization domain of HSF2 and the N-terminal hydrophilic region of HSF2BP.,tissue specificity:Testis specific., |
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