Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human HSPBP1
Specificity
This antibody detects endogenous levels of HSPBP1 at Human, Mouse,Rat
Gene Name
HSPBP1 HSPBP PP1845
Protein Name
Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-binding protein 2) (HspBP2) (Hsp70-interacting protein 1) (Hsp70-interacting protein 2)
Other Name
Species
Human
Gene ID
23640
Uniprot
Q9NZL4,
Species.1
Mouse
Gene ID.1
66245
Uniprot.1
Q99P31,
Species.2
Rat
Gene ID.2
246146
Uniprot.2
Q6IMX7
Cellular Localization
Tissue Expression
Ubiquitous.
Signaling_pathway
Genetic Information Processing >> Folding, sorting and degradation >> Protein processing in endoplasmic reticulum
Research Areas
Function
Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.