SKU: WP7139 Categories: ,

HSPBP1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7139-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetHSPBP1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)39kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human HSPBP1
SpecificityThis antibody detects endogenous levels of HSPBP1 at Human, Mouse,Rat
Gene NameHSPBP1 HSPBP PP1845
Protein NameHsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-binding protein 2) (HspBP2) (Hsp70-interacting protein 1) (Hsp70-interacting protein 2)
Other Name
SpeciesHuman
Gene ID23640
UniprotQ9NZL4,
Species.1Mouse
Gene ID.166245
Uniprot.1Q99P31,
Species.2Rat
Gene ID.2246146
Uniprot.2Q6IMX7
Cellular Localization
Tissue ExpressionUbiquitous.
Signaling_pathwayGenetic Information Processing >> Folding, sorting and degradation >> Protein processing in endoplasmic reticulum
Research Areas
FunctionInhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.
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