HSPBP1 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | HSPBP1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 39kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human HSPBP1 |
| Specificity | This antibody detects endogenous levels of HSPBP1 at Human, Mouse,Rat |
| Gene Name | HSPBP1 HSPBP PP1845 |
| Protein Name | Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-binding protein 2) (HspBP2) (Hsp70-interacting protein 1) (Hsp70-interacting protein 2) |
| Other Name | |
| Species | Human |
| Gene ID | 23640 |
| Uniprot | Q9NZL4, |
| Species.1 | Mouse |
| Gene ID.1 | 66245 |
| Uniprot.1 | Q99P31, |
| Species.2 | Rat |
| Gene ID.2 | 246146 |
| Uniprot.2 | Q6IMX7 |
| Cellular Localization | |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | Genetic Information Processing >> Folding, sorting and degradation >> Protein processing in endoplasmic reticulum |
| Research Areas | |
| Function | Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR. |
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