iASPP rabbit pAb
Ucallm_WP6466-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | PPP1R13L |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 91kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human iASPP |
| Specificity | This antibody detects endogenous levels of iASPP at Human, Mouse |
| Gene Name | PPP1R13L IASPP NKIP1 PPP1R13BL RAI |
| Protein Name | RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein) |
| Other Name | |
| Species | Human |
| Gene ID | 10848 |
| Uniprot | Q8WUF5, |
| Species.1 | Mouse |
| Gene ID.1 | 333654 |
| Uniprot.1 | Q5I1X5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus . Predominantly cytoplasmic but also nuclear. . |
| Tissue Expression | Highly expressed in heart, placenta and prostate. Weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte. |
| Signaling_pathway | |
| Research Areas | |
| Function | Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis . |
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