Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is a peptidyl-tRNA hydrolase and a vital component of the large mitochondrial ribosome. The encoded protein serves as a ribosome release factor for this ribosome, which translates mitochondrial genes. This protein may be responsible for degrading prematurely-terminated polypeptides and for reusing stalled ribosomes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014],
| Size | 50μL/100μL |
| Target | ICT1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 23kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ICT1 AA range: 7-57 |
| Specificity | This antibody detects endogenous levels of ICT1 at Human/Mouse |
| Gene Name | ICT1 DS1 |
| Protein Name | ICT1 |
| Other Name | |
| Species | Human |
| Gene ID | 3396 |
| Uniprot | Q14197, |
| Species.1 | Mouse |
| Gene ID.1 | 68572 |
| Uniprot.1 | Q8R035 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Mitochondrion . |
| Tissue Expression | Down-regulated during the in vitro differentiation of HT29-D4 colon carcinoma cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the prokaryotic/mitochondrial release factor family.,tissue specificity:Down-regulated during the in vitro differentiation of HT29-D4 colon carcinoma cells., |
