Product details
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IFT81 rabbit pAb
Ucallm_WP5978-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | IFT81 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 74kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human IFT81 |
| Specificity | This antibody detects endogenous levels of IFT81 at Human, Mouse,Rat |
| Gene Name | IFT81 CDV1 |
| Protein Name | Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1) |
| Other Name | |
| Species | Human |
| Gene ID | 28981 |
| Uniprot | Q8WYA0, |
| Species.1 | Mouse |
| Gene ID.1 | 12589 |
| Uniprot.1 | O35594, |
| Species.2 | Rat |
| Gene ID.2 | 373066 |
| Uniprot.2 | P83829 |
| Cellular Localization | Cell projection, cilium . Cytoplasm . |
| Tissue Expression | Highly expressed in testis, moderately in ovary, heart, liver, skeletal muscle, kidney and pancreas, low in prostate, brain, placenta and lung and not detected in spleen, thymus, small intestine and colon. Isoform CDV-1R is abundantly expressed in testis. |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region . Required for ciliogenesis . Required for proper regulation of SHH signaling . Plays an important role during spermatogenesis by modulating the assembly and elongation of the sperm flagella (By similarity). |
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