IKZF5 rabbit pAb
Ucallm_WP3936-50
Price range: $268.00 through $328.00
Product details
Background:
Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Pegasus, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM, Jul 2002],
Specifications
| Size | 50μL/100μL |
| Target | IKZF5 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 46kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human IKZF5 AA range: 210-260 |
| Specificity | This antibody detects endogenous levels of IKZF5 at Human/Mouse |
| Gene Name | IKZF5 ZNFN1A5 |
| Protein Name | IKZF5 |
| Other Name | |
| Species | Human |
| Gene ID | 64376 |
| Uniprot | Q9H5V7, |
| Species.1 | Mouse |
| Gene ID.1 | 67143 |
| Uniprot.1 | Q8BU00 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Expressed in brain, heart, skeletal muscle, kidney, and liver. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K-562. Highly expressed in THP-1 and M-07e cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively. |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:C-terminal zinc fingers mediate homodimerization.,Domain:The N-terminal zinc fingers are involved in sequence-specific DNA binding and heterotypic associations with other family members.,Function:DNA-binding protein that binds to the 5'GNNTGTNG-3' core sequence. Transcriptional repressor.,miscellaneous:'Pegasus' was the winged horse in Greek mythology.,similarity:Belongs to the Ikaros C2H2-type zinc-finger protein family.,similarity:Contains 5 C2H2-type zinc fingers.,subunit:Self-associates and interacts with other family members; IKZF1, IKZF2, IKZF3 AND IKZF4.,tissue specificity:Expressed in brain, heart, skeletal muscle, kidney, and liver. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K562. Highly expressed in THP-1 and Mo7e-IL3 cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively., |
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