SKU: WP12822 Categories: ,

IL-32 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12822-100
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Product details

Background:

This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetIL-32
ReactivityHuman
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)26kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human IL-32. AA range:177-226
SpecificityIL-32 Polyclonal Antibody detects endogenous levels of IL-32 protein.
Gene NameIL32
Protein NameInterleukin-32
Other NameIL32; / NK4; / TAIF; / Interleukin-32; / IL-32; / Natural killer cells protein 4; / Tumor necrosis factor alpha-inducing factor
SpeciesHuman
Gene ID9235
UniprotP24001
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted .
Tissue ExpressionSelectively expressed in lymphocytes. Expression is more prominent in immune cells than in non-immune cells.
Signaling_pathwayEnvironmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Research Areas>>Cytokine-cytokine receptor interaction
FunctionCaution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,Function:Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK.,induction:Expression increased after activation of T-cells by mitogens or activation of NK cells by IL-2.,tissue specificity:Selectively expressed in lymphocytes. Expression more prominent in immunce cells than in non-immune cells.,
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