SKU: WP15772 Categories: ,

Imp3 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP15772-100
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Product details

Background:

This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetIMP3
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, ELISA
MW(Calculated)
MW(Observed)25kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:200-1:1000; WB 1:500-2000; ELISA 1:10000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthetic peptide from human protein at AA range: 135-184
SpecificityThe antibody detects endogenous Imp3 protein
Gene NameIMP3 C15orf12 MRPS4
Protein NameU3 small nucleolar ribonucleoprotein protein IMP3
Other NameIMP 3; / IMP-3; / U3 small nucleolar ribonucleoprotein protein IMP3; / C15orf12; / MRPS4; / U3 snoRNP protein IMP3; / BRMS2
SpeciesHuman
Gene ID55272
UniprotQ9NV31,
Species.1Mouse
Gene ID.1102462
Uniprot.1Q921Y2
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus, nucleolus .
Tissue ExpressionEye,Placenta,Uterus,
Signaling_pathway
Research Areas>>Ribosome biogenesis in eukaryotes
FunctionFunction:Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.,similarity:Belongs to the ribosomal protein S4P family.,similarity:Contains 1 S4 RNA-binding domain.,subunit:Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10. Interacts with MPHOSPH10.,
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