SKU: WP12839 Categories: ,

InsP6 Kinase 3 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12839-100
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Product details

Background:

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1, 3, 4, 5, 6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008],

Specifications

Size50μL/100μL
TargetInsP6 Kinase 3
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)51kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human IP6K3. AA range:201-250
SpecificityInsP6 Kinase 3 Polyclonal Antibody detects endogenous levels of InsP6 Kinase 3 protein.
Gene NameIP6K3
Protein NameInositol hexakisphosphate kinase 3
Other NameIP6K3; / IHPK3; / Inositol hexakisphosphate kinase 3; / InsP6 kinase 3; / Inositol hexaphosphate kinase 3
SpeciesHuman
Gene ID117283
UniprotQ96PC2,
Species.1Mouse
Gene ID.1271424
Uniprot.1Q8BWD2
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm .
Tissue ExpressionDetected in brain.
Signaling_pathway
Research Areas>>Phosphatidylinositol signaling system
FunctionCatalytic activity:ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown).,Catalytic activity:ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.,Function:Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.,similarity:Belongs to the inositol phosphokinase (IPK) family.,tissue specificity:Detected in brain.,
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