INTU rabbit pAb
Ucallm_WP8558-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | INTU |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 104kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human INTU |
| Specificity | This antibody detects endogenous levels of INTU at Human, Mouse,Rat |
| Gene Name | INTU KIAA1284 PDZD6 PDZK6 |
| Protein Name | Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6) |
| Other Name | |
| Species | Human |
| Gene ID | 27152 |
| Uniprot | Q9ULD6, |
| Species.1 | Mouse |
| Gene ID.1 | 380614 |
| Uniprot.1 | Q059U7, |
| Species.2 | Rat |
| Gene ID.2 | 361938 |
| Uniprot.2 | D4ACE5 |
| Cellular Localization | Cytoplasm . Cell surface . Cytoplasm, cytoskeleton, cilium basal body . Enriched at the apical surface in ciliated cells. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies . |
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