Product details
Background:
ITGA8 (heavy chain, Cleaved-Arg906) rabbit pAb
Ucallm_WP0161-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ITGA8 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| MW(Calculated) | |
| MW(Observed) | 95kD,115kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ITGA8 (heavy chain, Cleaved-Arg906) |
| Specificity | This antibody detects endogenous levels of Human,Mouse,Rat ITGA8 (heavy chain, Cleaved-Arg906, protein was cleaved amino acid sequence between 906-907 ) |
| Gene Name | ITGA8 |
| Protein Name | ITGA8 (heavy chain, Cleaved-Arg906) |
| Other Name | Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; / Integrin alpha-8 light chain] |
| Species | Human |
| Gene ID | 8516 |
| Uniprot | P53708, |
| Species.1 | Mouse |
| Gene ID.1 | 241226 |
| Uniprot.1 | A2ARA8 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass type I membrane protein . Cell membrane . |
| Tissue Expression | Expressed in mesenchymal cells, including alveolar myofibroblasts, kidney mesangial cells and hepatic stellar cells and vascular and visceral smooth muscle (at protein level). |
| Signaling_pathway | Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion;Cellular Processes >> Cell motility >> Regulation of actin cytoskeleton;Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> ECM-receptor interaction;Environmental Information Processing >> Signaling molecules and interaction >> Cell adhesion molecules |
| Research Areas | >>PI3K-Akt signaling pathway; / >>Focal adhesion; / >>ECM-receptor interaction; / >>Cell adhesion molecules; / >>Regulation of actin cytoskeleton; / >>Human papillomavirus infection; / >>Hypertrophic cardiomyopathy; / >>Arrhythmogenic right ventricular cardiomyopathy; / >>Dilated cardiomyopathy |
| Function |
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