SKU: WP0173 Categories: ,

Kallikrein-7 (Cleaved-Ile30) rabbit pAb

Price range: $268.00 through $328.00

SKU: WP0173-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetKallikrein-7
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC
MW(Calculated)
MW(Observed)25kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human Kallikrein-7 (Cleaved-Ile30)
SpecificityThis antibody detects endogenous levels of Human,Mouse,Rat Kallikrein-7 (Cleaved-Ile30, protein was cleaved amino acid sequence between 29-30 )
Gene NameKLK7 PRSS6 SCCE
Protein NameKallikrein-7 (Cleaved-Ile30)
Other NameKallikrein-7; / hK7; / Serine protease 6; / Stratum corneum chymotryptic enzyme; / hSCCE
SpeciesHuman
Gene ID5650
UniprotP49862,
Species.1Mouse
Gene ID.123993
Uniprot.1Q91VE3,
Species.2Rat
Gene ID.224523
Uniprot.2P36373
Cellular LocalizationSecreted . In ovarian carcinoma, secreted and also observed at the apical membrane and in cytoplasm at the invasive front.
Tissue ExpressionAbundantly expressed in the skin and is expressed by keratinocytes in the epidermis. Also expressed in the brain, mammary gland, cerebellum, spinal cord and kidney. Lower levels in salivary glands, uterus, thymus, thyroid, placenta, trachea and testis. Up-regulated in ovarian carcinoma, especially late-stage serous carcinoma, compared with normal ovaries and benign adenomas (at protein level).
Signaling_pathway
Research Areas
Function
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