Product details
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KCND3 rabbit pAb
Ucallm_WP5056-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | KCND3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 72kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human KCND3 AA range: 91-141 |
| Specificity | This antibody detects endogenous levels of human KCND3 |
| Gene Name | KCND3 |
| Protein Name | Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3) |
| Other Name | |
| Species | Human |
| Gene ID | 3752 |
| Uniprot | Q9UK17, |
| Species.1 | Mouse |
| Gene ID.1 | 56543 |
| Uniprot.1 | Q9Z0V1, |
| Species.2 | Rat |
| Gene ID.2 | 56543 |
| Uniprot.2 | Q62897 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Cell membrane, sarcolemma; Multi-pass membrane protein . Cell projection, dendrite . Interaction with palmitoylated KCNIP2 and KCNIP3 enhances cell surface expression. . |
| Tissue Expression | Highly expressed in heart and brain, in particular in cortex, cerebellum, amygdala and caudate nucleus. Detected at lower levels in liver, skeletal muscle, kidney and pancreas. Isoform 1 predominates in most tissues. Isoform 1 and isoform 2 are detected at similar levels in brain, skeletal muscle and pancreas. |
| Signaling_pathway | Human Diseases >> Neurodegenerative disease >> Spinocerebellar ataxia |
| Research Areas | >>Spinocerebellar ataxia |
| Function |
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